SEINE PHARMA, WHAT WE OFFER

WHAT WE OFFER

  • Synthesis of impurity standards and reference standards
  • Synthesis of metabolites and degradation impurities
  • Synthesis of genotoxic impurities
  • Synthesis of APIs and advanced intermediates
  • Stable isotope labelled compounds
  • Customized Synthesis of NCEs
  • Development of new synthetic routes
  • Process Development
  • Peptide Synthesis

REFERENCE STANDARDS AND IMPURITY STANDARDS

We offer an extensive catalogue (more than 4000 impurities) for immediate shipment. Where stock is unavailable, we will undertake production of new impurities upon customer request. An uncompromising level of quality is offered for each impurity standard provided. Every standard produced is accompanied with a complete Certificate of Analysis (COA) and supported by comprehensive analytical data. We listen carefully to the concerns and needs of customers, and address each promptly and efficiently. We have a facility which follows GLP/GMP and is accredited by ISO 9001:2015, ISO 17025 especially for impurity synthesis. We also offer Primary Reference Standards of United States Pharmacopoeia (USP), European Pharmacopoeia (EP), British Pharmacopoeia (BP), Japanese Pharmacopoeia (JP), Indian Pharmacopoeia (IP) at very competitive prices.

SEINE PHARMA, REFERENCE STANDARDS AND IMPURITY STANDARDS
SEINE PHARMA, REACTION CAPABILITIES

REACTION CAPABILITIES

  • Grignard Reactions
  • Friedel-craft reactions
  • LiAlH4, NaCNBH3 based reactions
  • n-Butyl lithium and LDA reactions
  • NaH / KH, Sodium/Potassium alkoxide, Sodamide reactions
  • Reaction containing catalyst like Pd/C, PtO2, Raney-Nickel
  • Halogenation reactions (chlorination, bromination and iodination)
  • General protection and deprotection of functional groups
  • High pressure reactions
  • Reaction containing lacrimatic, corrosive, moisture sensitive, hazardous reagents
  • Suzuki, Heck, Stile reactions
  • Asymmetric synthesis & resolution of enantiomers
  • Deuterium Chemistry
  • Organometallic chemistry
  • Microwave assisted organic synthesis
  • Metal mediated organic transformations
  • Photochemical reactions
  • Enzymatic reactions
  • Peptide synthesis
  • Enzymatic synthesis
  • Chiral synthesis
 
 

ISOLATION OF UNKNOWN IMPURITIES AND DEGRADANTS

We have considerable expertise in the identification and isolation of new and challenging degradants and unknown impurities. We can provide expert advice on the mechanism of degradant formation and advise on modifications to formulations to reduce their levels. We can even design synthesis of these degradants in cost effective manner to reduce the project cost of our client.

SEINE PHARMA, ISOLATION OF UNKNOWN IMPURITIES AND DEGRADANTS

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